What Your Favorite WAIFU Says About You! Believe it or not, this video has over THREE MILLION views! It's pure crap, but I guess it's a topic which is of interest to some people. Just the same, you probably want to know what WAIFU means: Waifu is a joke word that Anime fans call fictional female characters that they love and would marry if they were real. So, maybe it's kind of like MILF (Mom I'd Like to Fuck) and more a topic of conversation - as in a bunch of guys joking about friends' moms - than an actual preoccupation or obsession.